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Book Details :
Published on: 2013-10-04
Released on: 2013-10-04
Original language: English

In recent years, there has been rapid growth in knowledge pertaining to the nervous system. This has, in some measure, been due to the development and application of a number of techniques such as the 2-deoxyglucose method and microchemical methods for measuring metabolites and regional cerebral blood flow. Data from the application of these techniques are just beginning to be collected, and the next few years promise to bring many new and exciting findings. The study of energy metabolism in brain is particularly interesting due to the fact that although the brain has scant energy reserves (as compared with the liver), it has one of the highest metabolic rates in the body. Recent studies from several laboratories have shown a surprising divergence of re­ sponses to metabolic insult in different areas of brain. In this regard, the cer­ ebellum, for example, may have metabolic features which are uniqve from those of any other region. The high-energy phosphate compounds ATP and phos­ phocreatine, supplied by the oxidative metabolism of glucose, are necessary for normal cerebral functions such as the maintenance of membrane potentials, transmission of impulses, and synthetic processes. Interruption of substrate or "poisoning" of the system by a variety of means lead to a rapid change in cellular energetics, and ultimately cell death. From the clinical standpoint, an interesting feature of metabolic encephalopathy is that in many cases, early diagnosis and treatment may result in a rapid reversal of symptoms. All Disorders National Institute of Neurological ... Disorders. All Disorders. NINDS Cerebral Cavernous Malformation Information Page; NINDS Encephalitis Lethargica Information Page; NINDS Epilepsy Information Page Metabolic encephalopathy definition of metabolic ... coma or its precursors resulting from a diffuse abnormality of cerebral neuronal or glial cell metabolism. Primary metabolic encephalopathy is due to any of the ... Inborn Metabolic Diseases - Diagnosis and Treatment Jean ... Inborn Metabolic Diseases Diagnosis and Treatment. Editors: Saudubray Jean-Marie Baumgartner Matthias R. Walter John (Eds.) Mitochondrial Function and Toxicity: Role of the B Vitamin ... 1. Introduction. The aim of this review is to better understand the relationship between clinical outcome and underlying mitochondrial disturbances due to B vitamin ... Inborn Errors of Metabolism in Infancy: A Guide to ... inborn errors of metabolism; inherited metabolic disorders; The number complexity and varied clinical presentation of inborn errors of metabolism present a ... Metabolic demand definition of metabolic demand by ... metabolic demand Abbreviation: Q/VO 2. The cardiac output divided by the oxygen uptake. See also: demand Acute Hyperammonemic Encephalopathy in Adults: Imaging ... Patients with acute hyperammonemic encephalopathy present with progressive drowsiness seizures and coma due to primary toxic effects of ammonia on the ... Hepatic EncephalopathyA Serious Complication of Alcoholic ... Hepatic EncephalopathyA Serious Complication of Alcoholic Liver Disease Roger F. Butterworth Ph.D. D.Sc. Roger F. Butterworth Ph.D ... Cerebral Edema : American Journal of Roentgenology: Vol ... This article reviews the pathophysiology and imaging appearances of cerebral edema or increased water content. Edema is a common response to various forms of brain ... ICD-10 Chapter IV: Endocrine nutritional and metabolic ... The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs symptoms abnormal ...
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